DLL1 K562
CBP74601
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| I. Background | |
| DLL1基因编码Delta样蛋白1(Delta-like protein 1),是Notch信号通路中一个至关重要的配体。 它顺利获得与邻近细胞表面的Notch受体(主要为NOTCH1、NOTCH2和NOTCH3)结合,激活下游信号,从而在细胞间通讯中发挥核心作用,调控细胞的分化、增殖和命运决定。DLL1在胚胎发育、神经系统形成、肌肉发生、免疫系统发育以及成体干细胞维持等多个生理过程中均扮演着不可或缺的角色。 | |
| II. Description | |
| DLL1 K562细胞,在 K562细胞的基础上,稳定表达 DLL1 。 | |
| III. Introduction | |
| Expressed gene: | DLL1 |
| Host Cell: | K562 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | RPMI-1640+10%FBS+2 μg/ml Puromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
Figure 1. Recombinant DLL1 K562 constitutively expressing DLL1. |
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